Browsing Articles, Conference and Workshop Papers Collection by Subject "Antimalarials"

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Molecular monitoring of resistant dhfr and dhps allelic haplotypes in Morogoro and Mvomero districts in south eastern Tanzania

Malisa, Allen L.; Pearce, R.; Abdullah, S.; Mutayoba, B.; Mshinda, H.; Kachur, P.; Bloland, P.; Roper, C. (African Health Sciences, 2011)

Background: Resistance to the antimalarial drug sulfadoxine-pyrimethamine (SP) emerged in Plasmodium falciparum from Asia in the 1960s and subsequently spread to Africa. In Tanzania, SP use as a national policy began in ...
Therapeutic efficacy of sulfadoxine-pyrimethamine and prevalence of resistance markers in Tanzania prior to revision of malaria treatment policy: Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase mutations in monitoring in vivo resistance

Mugittu, Kefas; Ndejembi, Modesta; Malisa, Allen; Lemnge, Martha; Premji, Zulfikar; Mwita, Alex; Nkya, Watoky; Kataraihya, Johannes; Abdulla, Salim; Beck, Hans-Peter; Mshinda, Hassan (The American Society of Tropical Medicine and Hygiene, 2004)

Prior to the 2001 malarial treatment policy change in Tanzania, we conducted trials to assess the efficacy of sulfadoxine-pyrimethamine (SP) and the usefulness of molecular markers in monitoring resistance. A total of ...

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